The MIT team wanted to come up with something that would work much faster. Existing tissue glues diffuse adhesive molecules through the water between two tissue surfaces to bind them together, but this process can take several minutes or even longer. Other authors are MIT graduate student Xinyu Mao, MIT assistant professor of mechanical engineering Ellen Roche, Mayo Clinic critical care physician Christoph Nabzdyk, and Brigham and Women’s Hospital pathologist Robert Padera.įorming a tight seal between tissues is considered to be very difficult because water on the surface of the tissues interferes with adhesion. Graduate students Hyunwoo Yuk and Claudia Varela are the lead authors of the study, which appears today in Nature. In addition, it works much faster than tissue glues, which usually take several minutes to bind tightly and can drip onto other parts of the body. The double-sided tape can also be used to attach implantable medical devices to tissues, including the heart, the researchers showed. We are proposing a fundamentally different approach to sealing tissue,” says Xuanhe Zhao, an associate professor of mechanical engineering and of civil and environmental engineering at MIT and the senior author of the study.
“There are over 230 million major surgeries all around the world per year, and many of them require sutures to close the wound, which can actually cause stress on the tissues and can cause infections, pain, and scars. They hope that this tape could eventually be used in place of surgical sutures, which don’t work well in all tissues and can cause complications in some patients. In tests in rats and pig tissues, the researchers showed that their new tape can tightly bind tissues such as the lungs and intestines within just five seconds. Inspired by a sticky substance that spiders use to catch their prey, MIT engineers have designed a double-sided tape that can rapidly seal tissues together.
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